Jeenomics, the NGS Laboratory is recognised by DSIR (Department of Science and Technology, Government of India) as SIRO and has a dedicated team of scientists involved in meaningful research that, in future can shape the way the patients are treated. Find below some of the recent publications and research work in progress.
List of Publications/Submissions (2014-2020)
- Martin Maiers, Michael Halagan, Sangeeta Joshi, H Sudarshan Ballal, LathaJagannatthan, SharatDamodar, Periathiruvadi Srinivasan,Saranya Narayan, NavinKhattry, Pankaj Malhotra, Ranjana W Minz, Sandip A Shah, Raghu Rajagopal, NezihCereb, Soo Young Yang,Sunil Parekh, Joy Mammen, Dolly Daniels, Daniel Weisdorf. HLA match likelihoods for Indian patients seeking unrelated donor transplantation grafts: a population-based studyLancet Haematol. 2014.1(2):e57-63. doi: 10.1016/S2352-3026(14)70021-3. Epub 2014 Oct 21.
- • Vikram Haridas, Praveenkumar Shetty, M Nirmal Kumar, KC Vasanthakumar, Kiran Haridas, VitthalKhode, Anil Bargale. Human leukocyte Antigen-B*27 allele subtype prevalence and disease association of ankylosing spondylitis among south Indian population. Indian Journal of Rheumatology. 2018.13(1):38-43.
- Srinivasan P. Urgent need for a South Asian Hematopoietic stem cell donor registry. Global J Transfus Med. 2018. 3:56-58
- Seshasubramanian Vani, Manisekar Nirmal Kumar, SathishkannanAruna Devi, NaganathanChandramouleeswaran and Narayan Saranya. Next Generation Sequencing in HLA Haplotype distribution among Telugu Speaking Population from South India. Human Immunology. 2018. 79(8):583-584. https://doi.org/10.1016/j.humimm.2018.05.005.
- Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar and Saranya Narayan. Urdu Speaking Population from South India. 6 extended haplotypes in linkage disequilibrium in Urdu Speaking Population of South India. HLA. 2018. 92:266-268. doi: 10.1111/tan.13326.
- Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar and Saranya Narayan. Kannadigas from South India: Extended haplotypes in Linkage disequilibrium in Kannadigas of South India. HLA.2018. 92:193-195. doi: 10.1111/tan.13324.
- • Saranya Narayan; Martin Maiers; Mike Halagan; ArunadeviSathishkannan; ChandramouleeswaranNaganathan; AbeerMadbouly. HLA-A, -B, -C, -DRB1 and –DQB1 haplotype frequencies from 2492 Cord Blood Units from Tamil speaking population from Tamil Nadu, India. Molecular Biology reports.2018. https://doi.org/10.1007/s11033-018-4382-6.
- • Vani Seshasubramanian, Nirmal Kumar Manisekar, Aruna Devi Sathishkannan, ChandramouleeswaranNaganathan, Yogesh Nandakumar, Saranya Narayan.Malayalam speaking population from South India: Common five-locus haplotypes in Malayalam speaking population.HLA.2018. 92:432-434. doi: 10.1111/tan.13389.
- Aarthi Manoharan, Ajay Sam Kumar, AmbujamSreedevi, Aruna Devi Sathishkannan, Bhargav Kiran Gaddam. HLA-B*5701 and HLA-B*5801 in an Indian patient with anti-epileptics induced cutaneous adverse drug reactions. European Journal of Clinical Pharmacology. 2018. 75:599-601. https://doi.org/10.1007/s00228-018-02618-5
- Vani Seshasubramanian, Aruna Devi SatishKannan, Chandramouleeswaran Naganathan, Nirmal Kumar Manisekar, Saranya Narayan. Identification of the novel HLA allele, HLA‐B*35:03:23, by next‐generation sequencing. HLA. 2019. 93(2-3):112-113. https://doi.org/10.1111/tan.13459
- Vani Seshasubramanian, Aruna Devi Satish Kannan, Chandramouleeswaran Naganathan, Yogesh NandakumarSaranya Narayan. Identification of the novel Allele, HLA‐B*40:379, by next‐generation sequencing.. HLA. 2019. 93(2-3):117-119 https://doi.org/10.1111/tan.13460.
- Vani,S., Meganathan,V., Nirmal Kumar,M., ArunaDevi,S., Chandramouleeswaran,N., Yogesh,N., Saranya,N. and Srinivasan,P. Application of high throughput Next Generation Sequencing for HLA typing of DNA extracted from post processing cord blood units. HLA. 2019. 94 (2)141–146. https://doi.org/10.1111/tan.13565
- Vani S, VijayaRaghavan, Aruna Devi S, Chandramouleeswaran N, Aparna R, Priya A, Preeti R, Sujit J, Brian M, Thara R, Saranya N, Srinivasan P. Association of HLA-A, -B, -C, -DRB1, and -DQB1 alleles and haplotypes with schizophrenia: A study from South India. International Journal of Immunogenetics
Novel HLA sequences submitted:
Gen bank No. | WHO (IMGT Nomenclature) | IMGT Assigned Date |
---|---|---|
MH192364 | B*40:379 | 30 Jul 2018 |
MH192365 | B*35:03:23 | 30 Jul 2018 |
MK854808 | DQB1*02:156 | 30 May 2019 |
MK854809 | B*35:455 | 30 May 2019 |
MN031261 | B*13:129 | 31 Jul 2019 |
MN056825 | DRB1*13:288 | 31 Jul 2019 |
MN067531 | DQB1*06:359 | 30 Sep 2019 |
MN337293 | B*38:02:08 | 30 Sep 2019 |
MN337294 | C*07:837 | 30 Sep 2019 |
MN337295 | DQB1*04:77 | 30 Sep 2019 |
MN337296 | C*12:304 | 30 Sep 2019 |
MN337297 | DQB1*06:142 | 30 Sep 2019 |
MN567304 | B*52:01:48 | 30 Nov 2019 |
MN565841 | B*58:121 | 31 Dec 2019 |
MN565840 | C*14:02:29 | 31 Dec 2019 |
MN565839 | A*01:291 | 30 Nov 2019 |
MN565839 | A*01:291 | 30 Nov 2019 |
MN565838 | Submitted | |
MN565837 | C*15:215 | 31 Mar 2020 |
MN565836 | Submitted | |
MN567302 | A*03:360 | 30 Nov 2019 |
MN565835 | Submitted | |
MN565834 | DQB1*05:01:40 | 31 Mar 2020 |
MN565833 | A*11:363 | 31 Mar 2020 |
MN567303 | B*52:95 | 31 Dec 2019 |
MT043141 | B*13:141 | 29 Feb 2020 |
MT043147 | B*38:167 | 29 Feb 2020 |
MT043140 | A*32:141 | 29 Feb 2020 |
MT043148 | C*12:03:29 | 29 Feb 2020 |
MT043142 | Submitted | |
MT043150 | Submitted | |
MT043143 | B*35:478 | 29 Feb 2020 |
MT043150 | Submitted | |
MT043144 | B*57:132 | 31 Mar 2020 |
MT043145 | B*50:01:16 | 31 Mar 2020 |
MT043146 | B*37:22:02 | 31 Mar 2020 |
MT043149 | Submitted |